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Biodistribution and pharmacokinetics of S 35 labeled 5

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Biodistribution and pharmacokinetics of 125I-labeled monoclonal antibody M75 specific for carbonic anhydrase IX, an intrinsic marker of hypoxia .

Previous article in issue: Increased toxicity and lack of efficacy of Rofecoxib in combination with chemotherapy for treatment of metastatic colorectal cancer: A phase II ... Cancer Diagnosis and Therapy Biodistribution and pharmacokinetics of 125 I-labeled ...

Pharmacokinetics, biodistribution, and stability oligodeoxynucleotide phosphorothioates in mi

Pharmacokinetics, biodistribution, andstability of oligodeoxynucleotide phosphorothioates in mice (antisense inhibition ofgene expression/antiviral therapy/oligodeoxynucleotide uptake/humaninimunodeficiency virus) ...

Phase I biodistribution and pharmacokinetic study of Lewis Y-targeting immunoconjugate CMD-193 in patients with advanced epithelial cancers .

Purpose: This phase I study explored the biodistribution and pharmacokinetics of the immunoconjugate CMD-193 ... The first cycle was trace labeled with (111)In for biodistribution assessment using gamma camera imaging. Subsequent cycles were depending ...

Biodistribution and pharmacokinetics of 188Re-liposomes and their comparative therapeutic efficacy with 5-fluorouracil in C26 colonic peritoneal .

effects. In the present study the biodistribution, pharmacokinetics, micro single-photon emission computed tomography (micro-SPECT/CT) image, dosimetry, and therapeutic efficacy of 188 Re-labeled nanoliposomes (188 Re-liposomes) in a C26 ...

Pharmacokinetics, biodistribution, and gamma camera imaging of 111In-KC-4G3 murine monoclonal antibody in athymic nude mice with or without human .

The pharmacokinetics and tissue distribution of the monoclonal antibody radioconjugate 111In-diethylenetriaminepentaacetic acid-KC-4G3, which is directed against a high molecular weight mucin(s) antigen expressed on the human milk fat globule and many ...

Enhanced tumor uptake, biodistribution and pharmacokinetics of etoposide loaded nanoparticles in Dalton's lymphoma tumor bearing mic

The purpose of this study is to determine and to compare the tumor uptake, biodistribution and pharmacokinetics of radiolabeled etoposide and etoposide loaded nanoparticles in Dalton's Lymphoma tumor bearing mice and healthy mice. Materials and Methods: ...

A phase I biodistribution and pharmacokinetic trial of humanized monoclonal antibody Hu3s193 in patients with advanced epithelial cancers that .

Patientswith advanced Le y-positive cancers received four infusions of hu3S193 at weekly intervals, with four dose levels (5, 10, 20, and 40 mg/m 2 ...

A Phase I Biodistribution and Pharmacokinetic Trial of Humanized Monoclonal Antibody Hu3s193 in Patients with Advanced Epithelial Cancers that .

antibody immunotherapy pharmacokinetics immune effector function biodistribution Biological Therapeutic Agents Phase I - III Clinical Trials Antibody immunotherapy Gamma camera scans IMMUNOLOGY The Lewis-y (Le y) antigen is a blood group–related antigen ...

Biodistribution and pharmacokinetics of 188Re-liposomes and their comparative therapeutic efficacy with 5-fluorouracil in C26 colonic peritoneal .

In the present study the biodistribution, pharmacokinetics, micro single-photon emission computed tomography (micro-SPECT/CT) image, dosimetry, and therapeutic efficacy of (188)Re-labeled nanoliposomes ((188) ...

Biodistribution, pharmacokinetics and imaging of 188Re-BMEDA-labeled pegylated liposomes after intraperitoneal injection in a C26 colon carcinoma .

35.54±5.17 19.52±2.21 2.45±0.56 1.46±0.11 0.29±0.06 Values were presented as % ID/g, mean±S.E.M. (n=4 at each time point). ... The biodistribution, pharmacokinetics and the imaging studies of RBLPL on the C26 colon carcinoma tumor ascites model ...

Quantitative Whole Body Biodistribution of Fluorescent-Labeled Agents by Non-Invasive Tomographic Imagi

5. Zhang Z, Liang K, Bloch S, Berezin M, Achilefu S (2005) Monomolecular multimodal fluorescence-radioisotope imaging agents. Bioconjug Chem 16: ...

Biodistribution and PET Imaging of pharmacokinetics of manganese in mice using Manganese-52(Journal Article) | DOE PAG

Pharmacokinetics, biodistribution, and stability of oligodeoxynucleotide phosphorothioates in mice ... (S)oligonucleotide ({sup 35}S-labeled at each internucleotide linkage) was found in most of the tissues for up to 48 hr. About 30% of the dose was excreted in ...

Biodistribution and PET Imaging of Labeled Bispecific T Cell–Engaging Antibody Targeting EpC

PET Acquisition Two mice were placed above each other in a Focus 220 rodent scanner (CTI Siemens), with the tumor in the field of view. Mice were kept warm on heating mats. Acquisition times differed between 10 min (0.5-h time point) and 75 min ...

University of Groningen Preclinical molecular imaging to study the biodistribution of antibody derivatives in oncology Warnders, Jan Fei

Biodistribution and PET imaging of labeled bispecific T cell–engaging antibody | 119 targeting EpCAM 118 | Chapter 5 ABSTRACT ... 5.35 ± 0.22 and 5.30 ± 0.20 percentage injected dose per gram; n = 3 and 4). Tumor uptake of 89Zr-AMG 110 was EpCAM ...

Genetically Engineered Tetravalent Single-Chain Fv of the Pancarcinoma Monoclonal Antibody CC49: Improved Biodistribution and Potential for .

Genetically Engineered Tetravalent Single-Chain Fv of the Pancarcinoma Monoclonal Antibody CC49: ... Pavlinkova G., Colcher D., Booth B. J. M., Goel A., Batra S. K. Pharmacokinetics and biodistribution of a light chain shuffled CC49 single-chain Fv antibody , ...

Biodistribution and pharmacokinetics of In-111-labeled Stealth{reg_sign} liposomes in patients with solid tumours (Journal Article) | OSTI.G

Harrington, K.J., Peters, A.M., & Mohammadtaghi, S. Biodistribution and pharmacokinetics of In-111-labeled Stealth{reg_sign} liposomes in patients with solid tumours. United States. Copy to clipboard ...

Uptake and Biodistribution of 89Zirconium-labeled Ipilimumab in Ipilimumab Treated Patients With Metastatic Melanoma - Full Text View .

Uptake and Biodistribution of 89Zirconium-labeled Ipilimumab in Ipilimumab Treated Patients With Metastatic Melanoma (Zirconipi) The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not ...

(PDF) Biodistribution and pharmacokinetics of S-35-labeled 5-thio-D-glucose in hamsters bearing pancreatic tumo

PDF | 5-thio-D-glucose (5-TDG) exerts profound effects on rapidly metabolizing tissues. We have used liquid scintillation counting to study the tissue distribution and pharmacokinetics of S-35-labeled 5-TDG in hamster models of pancreatic tumors. In the normal ...

Biodistribution and pharmacokinetics of S-35-labeled 5-thio-D-glucose in hamsters bearing pancreatic tumor

Markoe AM, Risch VR, Heindel ND, Emrich J, Lippincott W, Honda T, Brady LW. 5-thio-D-glucose (5-TDG) exerts profound effects on rapidly metabolizing tissues. We have used liquid scintillation counting to study the tissue distribution and pharmacokinetics of S-35-labeled 5-TDG in hamster models of

Image Guided Biodistribution and Pharmacokinetic Studies of Theranostics - Europe PMC Article - Europe PubMed Centr

Image guided technique is playing an increasingly important role in the investigation of the biodistribution and pharmacokinetics of drugs or drug delivery systems in various diseases, especially cancers. ...

Tuning Pharmacokinetics and Biodistribution of a ... - BioMedSearch - MAFIADOC.C

University, chongqing, People's republic of ... Chinese medicine for the treatment of inflammation, fever, ulcer, and cancer.1â 3 In recent years, a ..... of paclitaxel liposomes for lung targeting delivery in ...